Burkholderia Pseudomallei Ecology and Pathogenesis

Burkholderia pseudomallei is a soil-dwelling bacterium which causes the disease melioidosis. Endemic to southeast Asia, northern Australia, and other parts of the globe, B. pseudomallei is a pressing threat to global health and biosecurity.

Pathogenesis

As a pressing threat to global health and biosecurity, we study pathogenesis and ecology to develop new detection and therapeutic countermeasures for Bp.

Ecology

Our research identifies the components of the Type VI Secretion System required for host cell fusion and the association between fusogenic activity and virulence in Bp.

Therapeutics

Mapping Bp’s endemicity through ecological signatures from geographically separate regions, we’re building biocontrol strategies to eradicate Bp from endemic soil.

Funding Sources

Our generous sources of funding equip us to make new inroads into the study of melioidosis and Burkholderia pseudomallei.

Our Collaborators

Science is a team effort. We partner with experts in bacterial physiology, microbial ecology, clinical microbiology, and quantitative biology from institutions across the entire country.